Building on the seminal Mt. Amiata Project, the innovative Emptyscapes Project, and the initial work of Global Digital Heritage (GDH)) in southern Tuscany, a new form of transdisciplinary research is being developed. This project will transform the documentation, interpretation, and dissemination of the region's rich archaeological and historical heritage through interdisciplinary methodologies and the integration of advanced digital tools, including remote sensing, GIS, photogrammetry, and 3D visualization. This paper outlines the project's multi-scalar and diachronic approach to heritage analysis, emphasizing the interaction between digital technologies, historical reconstruction, and local community participation.